Walnut Oil Alleviates Intestinal Inflammation and Restores Intestinal Barrier Function in Mice
نویسندگان
چکیده
منابع مشابه
Epigenetic control of intestinal barrier function and inflammation in zebrafish.
The intestinal epithelium forms a barrier protecting the organism from microbes and other proinflammatory stimuli. The integrity of this barrier and the proper response to infection requires precise regulation of powerful immune homing signals such as tumor necrosis factor (TNF). Dysregulation of TNF leads to inflammatory bowel diseases (IBD), but the mechanism controlling the expression of thi...
متن کاملSodium butyrate protects the intestinal barrier function in peritonitic mice.
OBJECTIVE Peritonitis is a commonly seen disease with high morbidity and mortality. It is prevalently considered that the impaired intestinal barrier during peritonitis is the access point of gut microbes into the blood system, and acts as the engine of the following systemic infection. In our previous study, we found that Sodium Butyrate (NaB) was protective on intestinal barrier function. In ...
متن کاملProm1 Function in Development, Intestinal Inflammation, and Intestinal Tumorigenesis
Prom1/CD133 has been identified in colorectal, hepatocellular, and pancreatic cancer as a cancer stem cell marker and has been used as such to predict colon cancer recurrence in humans. Its potential molecular function as well as its role as a marker of intestinal regeneration is still not fully known. We evaluated the role of Prom1 in intestinal regeneration in inflammatory bowel disease (IBD)...
متن کاملCommentary: “Prom1 Function in Development, Intestinal Inflammation, and Intestinal Tumorigenesis”
A large body of publications mentioning prominin-1 (Prom1, CD133) is related to its use as a stem and cancer stem cell marker (1). Besides progenitor cells, its expression is widespread throughout terminally differentiated cells as those found in glandular organs (e.g., pancreas) and retina (2). Yet, the amino acid sequence of Prom1 didn’t reveal any motif or potential enzymatic activity that c...
متن کاملDietary fiber alleviates intestinal barrier dysfunction in post-trauma rats.
BACKGROUND Damage to the intestinal barrier often occurs following severe trauma. It has been reported that enteral nutrition with dietary fiber (DF) could mitigate impairment of the intestinal barrier and might therefore be effective in clinical application; however, the conclusions from existing trials are controversial and the nature of the protective mechanism is far from clear. This study ...
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ژورنال
عنوان ژورنال: Nutrients
سال: 2020
ISSN: 2072-6643
DOI: 10.3390/nu12051302